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[Functional and Stereotactic Neurosurgery] Technology & the Neurosurgery Operating Rooms:

Neuro Control Room | Surgical Planning & IGS | Stereotactic Neurosurgery
Intra-Operative MRI
| Intra-Operative CT | Intra-Operative Electrophysiology
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Intra-Operative Electrophysiology:
Deep Brain Stimulators for Parkinson's Disease:

Intra-Operative Electrophysiology: STN location
Stereotaxic Surgery
e-physiology cart
DBS placement


Deep Brain Stimulators for Parkinson's Disease
Mini Presentation (ppt) - Dr Emad Eskandar, MD

Subthalamic Stimulation For Parkinson’s Disease

  • The subthalamic nucleus (STN) is overactive in Parkinson’s Disease.
  • Placement of deep brain stimulators causes inactivation of subthalamic nucleus.
  • Deep brain stimulators are adjustable allowing for maximum benefit and minimal side-effects.
  • Early results are very promising.
  • STN is a small nucleus requiring advanced imaging and neurophysiologic techniques for optimal localization.

Localization of STN

  • Patients first undergo stereotactic localization using MRI and CT imaging to optimize localization.
  • The optimal location is confirmed by recording the activity of single neurons using an array of micro-electrodes.
  • Electrodes are advanced using a specialized microdrive.
  • Signal is displayed on a computer monitor and, as and audio signal.
  • Analysis of electrode recordings allows for high degree of precision in stimulator placement.
brain atlas e-physiology trace

Deep Brain Stimulation at MGH

  • No significant complications.
  • Early results are promising.
  • Future potential applications include treatment of dystonia, chronic pain, and depression.
  • Future improvements will involve correlating physiologic data with intra-operative CT and MRI.
Disclaimer About Medical Information: The information and reference materials contained herein is intended solely for the information of the reader. It should not be used for treatment purposes, but rather for discussion with the patient's own physician. All visitors to this and associated sites from the Neurosurgical Service at MGH agree to read and abide by the the complete terms of legal agreement found at the Neurosurgery "disclaimer & legal agreement." See also: the MGH Disclaimer, the MGH Privacy Policy, and the MGH Interactive Program Disclaimer - Copyright 2005.
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Last modified: June 23, 2006