Nicholas T. Zervas, M.D. Distinguished Higgins Professor of Neurosurgery Harvard Medical School Senior Attending Neurosurgeon, Massachusetts General Hospital E-Mail To: bperrier@partners.org Patient Appointments: 617-726-4141 Physician Referral: MGH Neurosurgery Referral System E-Mail Referral to: bperrier@partners.org Clinical Background - Curriculum vitae: MD Degree: University of Chicago School of Medicine 1954 Residency: Montreal Neurological Institute, Canada Neurology 1956 Massachusetts General Hospital Neurosurgery 1962 Board Certifications: Neurosurgery 1964

Surgical Interests:

• Pituitary Tumor Center and Neuroendocrine Clinical Center

Research Interests:

• Research@Neurosurgery
• Neurosurgery Surgical Research Laboratory
• Treatment of Post-Surgical Vasoconstriction
• Laboratory for Cerebrovascular Biophysics

Selected Recent Publications:

Swearingen B, et al.           [See Related Articles]

Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly.
J Clin Endocrinol Metab. 1998 Oct;83(10):3419-26.
PMID: 9768641; UI: 98439577.

Butler WE, et al.           [See Related Articles]

A mobile computed tomographic scanner with intraoperative and intensive care unit applications.
Neurosurgery. 1998 Jun;42(6):1304-10; discussion 1310-1.
PMID: 9632189; UI: 98293978.

Husain N, et al.           [See Related Articles]

Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines.
Acta Neuropathol (Berl). 1998 Mar;95(3):287-90.
PMID: 9542594; UI: 98203721.

Katznelson L, et al.           [See Related Articles]

Biochemical assessment of Cushing's disease in patients with corticotroph macroadenomas.
J Clin Endocrinol Metab. 1998 May;83(5):1619-23.
PMID: 9589666; UI: 98251577.

Moayeri NN, et al.           [See Related Articles]

Spinal dural enhancement on magnetic resonance imaging associated with spontaneous intracranial hypotension. Report of three cases and review of the literature.
J Neurosurg. 1998 May;88(5):912-8. Review.
PMID: 9576264; UI: 98235797.

Kawamata T, et al.           [See Related Articles]

Augmentation of both hemolysate-induced contraction and activation of protein kinase C by submaximum activation in canine cerebral arteries in vitro.
J Neurosurg. 1997 Dec;87(6):908-15.
PMID: 9384403; UI: 98044059.

Biller BM, et al.           [See Related Articles]

A decade of the Massachusetts General Hospital Neuroendocrine Clinical Center.
J Clin Endocrinol Metab. 1997 Jun;82(6):1668-74. No abstract available.
PMID: 9177360; UI: 97320509.

Cosgrove GR, et al.           [See Related Articles]

Interstitial irradiation of brain tumors, using a miniature radiosurgery device: initial experience.
Neurosurgery. 1997 Mar;40(3):518-23; discussion 523-5.
PMID: 9055291; UI: 97208055.

Hakim R, et al.           [See Related Articles]

Initial characterization of the dosimetry and radiology of a device for administering interstitial stereotactic radiosurgery.
Neurosurgery. 1997 Mar;40(3):510-6; discussion 516-7.
PMID: 9055290; UI: 97208054.

Manno EM, et al.           [See Related Articles]

The safety and efficacy of cyclosporine A in the prevention of vasospasm in patients with Fisher grade 3 subarachnoid hemorrhages: a pilot study.
Neurosurgery. 1997 Feb;40(2):289-93.
PMID: 9007860; UI: 97160360.

Sakas DE, et al.           [See Related Articles]

Perfluorocarbons: recent developments and implications for neurosurgery.
J Neurosurg. 1996 Aug;85(2):248-54. Review.
PMID: 8755753; UI: 96302289.

Sakas DE, et al.           [See Related Articles]

Stereotactic or stereotaxic: time to resolve the age-old controversy.
J Neurosurg. 1996 May;84(5):892-4. No abstract available.
PMID: 8622170; UI: 96198921.

Sakas DE, et al.           [See Related Articles]

Experimental microneurosurgery of the trigeminal nerve: surgical technique for ganglionectomy and rhizotomy in the cat.
J Neurosci Methods. 1996 Apr;65(2):137-41.
PMID: 8740590; UI: 96305692.

Bulter WE, et al.           [See Related Articles]

Intracellular calcium, myosin light chain phosphorylation, and contractile force in experimental cerebral vasospasm.
Neurosurgery. 1996 Apr;38(4):781-7; discussion 787-8.
PMID: 8692399; UI: 96247831.

Alexander JM, et al.           [See Related Articles]

Tumor-specific expression and alternate splicing of messenger ribonucleic acid encoding activin/transforming growth factor-beta receptors in human pituitary adenomas.
J Clin Endocrinol Metab. 1996 Feb;81(2):783-90.
PMID: 8636304; UI: 96225556.

Borges LF, et al.           [See Related Articles]

Idiopathic spinal cord herniation: a treatable cause of the Brown-Sequard syndrome--case report.
Neurosurgery. 1995 May;36(5):1028-32; discussion 1032-3.
PMID: 7791969; UI: 95312181.

Yokota M, et al.           [See Related Articles]

Protein kinase C and diacylglycerol content in basilar arteries during experimental cerebral vasospasm in the dog.
J Neurosurg. 1995 May;82(5):834-40.
PMID: 7714610; UI: 95230375.

Miller GM, et al.           [See Related Articles]

Somatostatin receptor subtype gene expression in pituitary adenomas.
J Clin Endocrinol Metab. 1995 Apr;80(4):1386-92.
PMID: 7714115; UI: 95229842.

Yamakawa K, et al.           [See Related Articles]

Effect of vasoconstrictor agents on diacylglycerol content of normal and vasospastic canine basilar arteries in vitro.
Neurosurgery. 1995 Apr;36(4):789-96.
PMID: 7596511; UI: 95319616.

Kaoutzanis MC, et al.           [See Related Articles]

Basic mechanism of in vitro pulsed-dye laser-induced vasodilation.
J Neurosurg. 1995 Feb;82(2):256-61.
PMID: 7815154; UI: 95114700.

Chiocca EA, et al.           [See Related Articles]

Deep sylvian fissure meningioma without dural attachment in an adult: case report.
Neurosurgery. 1994 Nov;35(5):944-6; discussion 946. Review.
PMID: 7838346; UI: 95140225.